Publications

Chemical Inhibition of Bromodomain Proteins in Insect-Stage African Trypanosomes Perturbs Silencing of the Variant Surface Glycoprotein Repertoire and Results in Widespread Changes in the Transcriptome

Published in Microbiology Spectrum, 2023

Investigating time-course transcriptional response to Bdf3 inhibition in the parasite that causes sleeping sickness.

Recommended citation: Ashby, Ethan C. (2023). "Chemical Inhibition of Bromodomain Proteins in Insect-Stage African Trypanosomes Perturbs Silencing of the Variant Surface Glycoprotein Repertoire and Results in Widespread Changes in the Transcriptome." Microbiology Spectrum. 1(1). https://journals.asm.org/doi/full/10.1128/spectrum.00147-23

Genomic Occupancy of the Bromodomain Protein Bdf3 Is Dynamic during Differentiation of African Trypanosomes from Bloodstream to Procyclic Forms

Published in MSphere, 2022

This paper is about the number 2. The number 3 is left for future work.

Recommended citation: Ashby, Ethan, et al. (2022). "Genomic Occupancy of the Bromodomain Protein Bdf3 Is Dynamic during Differentiation of African Trypanosomes from Bloodstream to Procyclic Forms." MSphere . 7(3). https://journals.asm.org/doi/full/10.1128/msphere.00023-22